CoNIFER 0.2.2 Beta
CoNIFER 0.2.2 Beta Full Download Summary
File size: 20 kB
Platform: WinXP, Windows Vista, Windows Vista x64, Windows 7, Windows 7 x64
License: Freeware
Price: FREE
Downloads: Total: 21 | This Month: 0
Released: 2012-09-24
Publisher: Niklas Krumm
Publisher URL: http://conifer.sourceforge.net/
CoNIFER 0.2.2 Beta Full Description
CoNIFER uses exome sequencing data to find copy number variants (CNVs) and genotype the copy-number of duplicated genes. As exome capture reactions are subject to strong and systematic capture biases between sample batches, we implemented singular value decomposition (SVD) to eliminate these biases in exome data.
CoNIFER offers the ability to mix exome sequence from multiple experimental runs by eliminating batch biases. Together with a short read aligner such as mrsFAST which can align reads to multiple locations, CoNIFER can robustly detect rare CNVs and estimate the copy number of duplicated genes up to ~8 copies with current exome capture kits. To get started right away, read the quick start guide.
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